Dr. Octavio Paredes López


Position: Investigador 3F, SNI III.
Telephone: +52 (462) 6239641, 674
Department: Biotechnology and Biochemistry,
Laboratory of Food Biotechnology

Research » Biotechnology and Biochemistry » Professors/Researchers » Dr. Paredes López Octavio

Education & training

1980    Ph.D. in Plant Science, Faculty of Agriculture, U. of Manitoba, Canada
1975    M.Sc.  Food Science, National Polytechnic Institute, Mexico
1970    M.Sc.  Biochemical Engineering, Czechoslovak Academy of Sciences, Czech Republic


Reseach interests

  • Biotechnology of food crops from Mesoamerica
  • Molecular biotechnology of food crops with nutraceutical interest
  • Expression of macromolecules with nutraceutical and medical interest

Recent publications  

  • Gustavo A. Camelo-Méndez, M. José Jara-Palacios, M. Luisa Escudero-Gilete, Belén Gordillo, Dolores Hernanz, Octavio Paredes-López, Pablo E. Vanegas-Espinoza, Alma A. Del Villar-Martínez, mailto:adelvillarm@ipn.mxFrancisco J. Heredia. Comparative Study of Phenolic Profile, Antioxidant Capacity, and Color-Composition Relation of Roselle Cultivars with Contrasting Pigmentation. Plant Foods for Human Nutrition. (2016), 1: 109-114.
  • Jocksan I. Morales-Camacho, Octavio Paredes-López, Edgar Espinosa-Hernández, Daniel Alejandro Fernández-Velasco, Silvia Luna-Suárez. Expression, Purification and Thermal Stability Evaluation of an Engineered Amaranth Protein Expressed in Escherichia coli. Electronic Journal of Biotechnology. (2016), 22: 44-51.
  • Maribel Valdez-Morales, L. Céspedes Carlos, María Elena Valverde, Enrique Ramírez-Chávez, Octavio Paredes López. Phenolic Compounds, Antioxidant Activity and Lipid Profile of Huitlacoche Mushroom (Ustilago maydis) Produced in Several Maize Genotypes at Different Stages of Development. Plant Foods for Human Consumption. (2016), 4: 436-443.
  • Ramona J. Espinoza-Moreno, Cuauhtémoc Reyes-Moreno, Jorge Milán-Carrillo, José A. López-Valenzuela, Octavio Paredes-López, Roberto Gutiérrez-Dorado. Healthy Ready-to-Eat Expanded Snack with High Nutritional and Antioxidant Value Produced from Whole Amarantin Transgenic Maize and Black Common Bean. Plant Foods for Human Nutrition. (2016), 2: 218-224.
  • Domancar Orona-Tamayo, María Elena Valverde, Blanca Nieto-Rendón, Octavio Paredes-López. (2015) Inhibitory activity of chia (Salvia hispanica L.) protein fractions against angiotensin I-converting enzyme and antioxidant capacity. LWT - Food Science and Technology, 64(1):236-242.
  • Gustavo A. Camelo-Méndez, M. José Jara-Palacios,  M. Luisa Escudero-Gilete, Belén Gordillo, Dolores Hernanz, Octavio Paredes-López, Pablo E. Vanegas-Espinoza, Alma A. Del Villar-Martínez y  Francisco J. Heredia.  (2015) Comparative Study of Phenolic Profile, Antioxidant Capacity, and Color-composition Relation of Roselle Cultivars with Contrasting Pigmentation. Plant Foods for Human Nutrition, 68(3):229-234.
  • Luis A. Bello-Pérez, Pamela C. Flores-Silva, Gustavo A. Camelo-Méndez, Octavio Paredes-López, Juan de Dios Figueroa-Cárdenas. (2015) Effect of the Nixtamalization Process on the Dietary Fiber Content, Starch Digestibility, and Antioxidant Capacity of Blue Maize Tortilla. Cereal Chemistry Journal. 92(3):365-270.
  • María Elena Valverde, Talía Hernández-Pérez, and Octavio Paredes-López. (2015) Edible Mushrooms: Improving Human Health and Promoting Quality Life. International Journal of Microbiology. 1-14.DOI. 10.1155/2015/376387
  • Michael A. Timmers, Jorge L. Guerrero-Medina, Debora Esposito, Mary H. Grace, Octavio Paredes-López, Pedro A. García-Saucedo y  Mary Ann Lila. (2015) Characterization of Phenolic Compounds and Antioxidant and Antiinflammatory Activities from Mamuyo (Styrax ramirezii Greenm.) Fruit. Journal of Agricultural and Food Chemistry.  63(48):10459-10465.
  • Árgel Gastelum-Arellanez, Octavio Paredes-López, Víctor Olalde-Portugal. (2014) Extracellular endoglucanase activity from Paenibacillus polymyxa BEb-40: production, optimization and enzymatic characterization. World Journal of Microbiology & Biotechnology, 30(11):2953-2965.
  • Israel Benítez-García, Pablo Emilio Vanegas-Espinoza, Antonio J. Meléndez-Martínez, Francisco J. Heredia, Octavio Paredes-López y  Alma Angélica Del Villar-Martínez. (2014) Callus culture development from two varieties of Tagetes erecta and carotenoids production. Electronic Journal of Biotechnology (2014), 17(3):107-103.
  • Oliviert Martínez-Cruz y Octavio Paredes-López. Phytochemical profile and nutraceutical potential of chia seeds (Salvia hispanica L.) by UPLC. Journal of Chromatography A., 1346:43-48.
  • P.I. Angulo-Bejarano, O. Martínez-Cruz and O. Paredes-López. (2014) Phytochemical content, nutraceutical potential and biotechnological applications of an ancient Mexican plant: nopal (Opuntia ficus-indica). Current Nutrition & Food Science, 10(3):196-217.
  • Cuauhtémoc Reyes-Moreno, Ana E. Ayala-Rodríguez, Jorge Milán-Carrillo, Saraid Mora-Rochín, José A. López-Valenzuela, Angel Valdez-Ortiz, Octavio Paredes-López, Roberto Gutiérrez-Dorado. (2013) Production of nixtamalized flour and tortillas from amarantin transgenic maize lime-cooked in a thermoplastic extruder. Journal of Cereal Science.  68(3):465–471.
  • G. A. Camelo-Méndez,  J. A. Ragazzo-Sánchez, A. R. Jiménez-Aparicio, P. E. Vanegas-Espinoza, O. Paredes-López, A. A. Del Villar-Martínez. (2013) Comparative study of anthocyanin and volatile compounds content of four varieties of Mexican roselle (Hibiscus sabdariffa L.) by multivariable analysis. Plant Foods for Human Nutrition. 68(3):229-234.
  • Jocksan Ismael Morales-Camacho, Jorge Domínguez-Domínguez and  Octavio Paredes-López. (2013) Overexpression of a modified amaranth protein in Escherichia coli with minimal media and lactose as inducer. Recent Patents on Biotechnology. 7(1):61-70.
  • María A. Nuñez-López, Octavio Paredes-López and  Rosalía Reynoso-Camacho. (2013) Functional and hypoglycemic properties of cladodes (O. ficus-indica) at different maturity stages using in vitro and in vivo tests. Journal of Agricultural of Food Chemistry. 61(46):10981-10986.
  • María R. Sandoval-Oliveros and Octavio Paredes-López. (2013) Isolation and characterization of proteins from chia seeds (Salvia hispanica L.). Journal of Agricultural and Food Chemistry.  61(1):193-201.
  • Sergio Medina-Godoy,  Silvia K. Rodríguez-Yáñez, Norma A. Bobadilla, Rosalba Pérez-Villalva, Rafael Valdés- Ortiz,  Enrique Hong, Silvia Luna-Suárez,  Octavio Paredes-López,  Ángel Valdez- Ortiz.  (2013) Antihypertensive activity of AMC3, an engineered 11S amaranth globulin expressed in Escherichia coli, in spontaneously hypertensive rats. Journal of Functional Foods. 5(3):1441-1449.
  • Andrés Cruz-Hernández and Octavio Paredes-López. (2012) Fruit quality: new insights for biotechnology. CRC Crit. Rev. Food Sci. Nutr.  52(3): 272-289.
  • Claudia Castro-Martínez, Silvia Luna-Suárez, Octavio Paredes-López. (2012) Overexpression of a modified protein from amaranth seed in Escherichia coli and effect of environmental conditions on the protein expression. J. Biotechnol. 158(1-2): 9-67.
  • Andrés Cruz-Hernández,  Octavio Paredes-López. (2011) Enhancement of economical value of nopal and its fruits through biotechnology. J. Prof. Assoc. Cactus Dev. 12(3):110-126.
  • M.C. Cano-Campos, S.P. Díaz-Camacho, M.J. Uribe-Beltrán, G. López-Angulo, J. Montes-Avila, O. Paredes-López, F. , Delgado-Vargas. (2011) Bio-guided fractionation of the antimutagenic activity of methanolic extract from the fruit of Randia echinocarpa (Sessé et Mociño) against 1-nitropyrene. Food Research. Inernational.  44: 3087-3093.
  • Pablo Emilio Vanegas-Espinoza, Verónica Ramos-Viveros,  Antonio Ruperto Jiménez-Aparicio, Oliver López-Villegas, Francisco José Heredia-Mira, Antonio Jesús Meléndez-Martínez, Adrián Guillermo Quintero-Gutiérrez,  Octavio Paredes-López,  Alma Angélica Del Villar-Martínez. (2011) Plastid analysis of pigmented undifferentiated cells of Marigold Tagetes erecta L. by transmission electron microscopy. In Vitro Cell. Dev. Biol.-Plant. 47:596-603.
  • Paola Isabel Angulo-Bejarano, Octavio Paredes-López. (2011) Development of a regeneration protocol through indirect organogenesis in prickly pear cactus (Opuntia ficus indica (L.) Mill). Scientia Hort.  128: 283-288.
  • Perla Osorio-Díaz, Edith Agama-Acevedo, Luis A. Bello-Pérez, José Juan Islas-Hernández, Noel O. Gómez-Montiel, Octavio Paredes-López. (2011) Effect of endosperm type on texture and in vitro starch digestibility of maize tortillas. LWT- Food Sci. Technol.  44(3):611-615.
  • Shela Gorinstein, Hanna Leontowickz, Maria Leontowickz, Katarzyna Najman, Wojciech Bielecki, Kyung-Sik Ham, Seong-Gook Kang, Octavio Paredes-Lopez, Alma Leticia Martinez-Ayala, Simon Trakhtenberg. (2011) Aorta and liver changes in rats fed cholesterol–containing and raw vegetable-supplemented diets: experiments in vitro and in vivo. J. Agric. Food Chem.   59:7441-7451.
  • Maribel Valdéz Morales, Kathleen Barry, George C. Fahey Jr, Jorge Domínguez, Elvira González de Mejía, María Elena Valverde y Octavio Paredes-López. (2010) Effect of maize genotype, developmental stage, and cooking process on the nutraceutical potential of huitlacoche (Ustilago maydis). Food Chem. 119(3):689-697.
  • Carlos L. Céspedes, Maribel Valdéz-Morales, José G. Ávila, Mohammed El-Hafidi, Julio Alarcón, Octavio Paredes-López.  (2010) Phytochemical profile and the antioxidant activity of Chilean wild black-berry fruits, Aristotelia chilensis (Mol) Stuntz (Elaeocarpaceae). Food Chem.  119(4): 886-895
  • Tarinee Tungsuchat-Huang, Sugey Ramona Sinagawa-García, Octavio Paredes-López, and Pal Maliga.  (2010) Study of plastid genome stability in tobacco reveals that the loss of marker genes is more likely by gene conversion than by recombination between 34-bp loxP repeats. Plant Physiol. 153(4): 252-259.
  • Tania Breshkovskaya Ortiz-Escobar, María Elena Valverde-González and Octavio Paredes-López. (2010) Determination of folate content in cladodes of nopal (Opuntia ficus indica) by microbiological assay utilizing Lactobacillus casei Casei (ATCC 7469) and ELISA.  J. Agric. Food Chem. 58(10): 6472-6475.
  • Edith O. Cuevas-Rodríguez, Gad G. Yousef, Pedro A. García-Saucedo, José López-Medina, Octavio Paredes-López, and Mary Ann Lila. (2010) Characterization of anthocyanins and proanthocyanidins in wild and domesticated Mexican blackberries (Rubus spp.). J. Agric. Food Chem. 58(12): 7458-7464.
  • Silvia Luna-Suárez, Sergio Medina-Godoy, Andrés Cruz-Hernández, Octavio Paredes-López. (2010) Modification of the amaranth 11S globulin storage protein to produce an angiotensin I converting enzyme inhibitory peptide, and its expression in E. coli. J. Biotechnol. 148(4):240-247.
  • Edith O. Cuevas-Rodri´guez, Vermont P. Dia, Gad G. Yousef,  Pedro. A García-Saucedo,  José Lo´pez-Medina, Octavio Paredes-López,  Elvira González de Mejía and Mary Ann Lila. (2010) Inhibition of pro-inflammatory responses and antioxidant capacity of Mexican blackberry (Rubus spp.) extracts. J. Agric. Food Chem. 58(17):9542-9548.




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