es-MXen-US

 

                               

DRA. GERTRUD LUND

Position: Investigador 3-D, SNI II

Telephone: +52 (462) 6239664

email: glund@ira.cinvestav.mx

Laboratory of Epigenetics
ResearchGate

 

 

EDUCATION & TRAINING

 

2011 - 2012    Visiting professor, IDIBELL, Bellvitge Biomedical Research Institute, Barcelona, ES
1998 - 2003    Associate professor, Dept. Of Plant Biochemisty, University of Copenhagen, DK
1995 - 1998    Post-doctorate, Dept. of Zoology & Plant Sciences, University of Oxford UK.
1995              Ph.D., Faculty of Life Sciences, Copenhagen, Denmark (experimental work at IBBA, Milan, Italy & Rutgers University, USA)
1991              M.Sc. Horticulture, Faculty of Life Sciences, Copenhagen, DK

RESEARCH INTERESTS

Natural methylation variation, dietary factors and DNA methylation, methylation and transition mutations  

 

RECENT PUBLICATIONS

  • Silva-Martínez GA,  Zaina S and Lund G. Array probe density and pathobiological relevant CpG calling bias in human disease and physiological DNA methylation profiling. 2017. Brief Funct Genomics elx017.
     
  • Zaina S, Lund G. Connecting the Dots Between Fatty Acids, Mitochondrial Function, and DNA Methylation in Atherosclerosis. 2017. Curr Atheroscler Rep.  19(9):36.
     
  • Lauria M, Echegoyen-Nava RA, Rodríguez-Ríos D, Zaina S, Lund G. Inter-individual variation in DNA methylation is largely restricted to tissue-specific differentially methylated regions in maize. BMC Plant Biol. 2017; 17(1):52. doi: 10.1186/s12870-017-0997-3.
     
  • Ciccarella G, Lund G, Zaina S. Trojan horses for drugs: a new role for lipoproteins? Curr Opin Lipidol. 2016; 27(6):638-639
     
  • Associations between whole peripheral blood fatty acids and DNA methylation in humans. de la Rocha C, Pérez-Mojica JE, León SZ, Cervantes-Paz B, Tristán-Flores FE, Rodríguez-Ríos D, Molina-Torres J, Ramírez-Chávez E, Alvarado-Caudillo Y, Carmona FJ, Esteller M, Hernández-Rivas R, Wrobel K, Wrobel K, Zaina S, Lund G. Sci Rep. 2016 May 16;6:25867.
     
  • Silva-Martínez GA, Rodríguez-Ríos D, Alvarado-Caudillo Y, Vaquero A, Esteller M, Carmona FJ, Moran S, Nielsen FC, Wickström-Lindholmx M, Wrobel K, Wrobel K, Barbosa-Sabanero G, Zaina S, Lund G. Arachidonic and oleic acid exert distinct effects on the DNA methylome. Epigenetics. 2016 Apr 18:0.
     
  • Flores-Sierra J, Arredondo-Guerrero M, Cervantes-Paz B, Rodríguez-Ríos D, Alvarado-Caudillo Y, Nielsen FC, Wrobel K, Wrobel K, Zaina S, Lund G. The trans fatty acid elaidate affects the global DNA methylation profile of cultured cells and in vivo. Lipids Health Dis. 2016 Apr 12;15(1):75. doi: 10.1186/s12944-016-0243-2.
     
  • de la Rocha C, Zaina S, Lund G. 3. Reprogramming transgenerational programming. Curr Opin Lipidol. 2015 Dec;26(6):603-4. doi: 10.1097/MOL.0000000000000245.
     
  • Valencia-Morales Mdel P, Zaina S, Heyn H, Carmona FJ, Varol N, Sayols S, Condom E, Ramírez-Ruz J, Gomez A, Moran S, Lund G, Rodríguez-Ríos D, López-González G, Ramírez-Nava M, de la Rocha C, Sanchez-Flores A, Esteller M. The DNA methylation drift of the atherosclerotic aorta increases with lesion progression. BMC Med Genomics. 2015 Feb 27;8:7. doi: 10.1186/s12920-015-0085-1.
     
  • Zaina S and Lund G (2014) Cardiovascular epigenome-wide association studies: is epigenetics falling short? Current Opinion in Lipidology 25:474-5.
     
  • Zaina S and Lund G (2014) Atherosclerosis: cell biology and lipoproteins - epigenetics and oxidation in atherosclerosis. Curr Opin Lipidol. 25(3):235-6.
     
  • Lauria M, Piccinini S, Pirona R, Lund G, Viotti A, Motto M (2014) Epigenetic variation, inheritance, and parent-of-origin effects of cytosine methylation in maize (Zea mays). Genetics. 196(3):653-66.
     
  • Zaina S, del Pilar Valencia-Morales M, Tristán-Flores FE, Lund G.
    Nuclear reprogramming and its role in vascular smooth muscle cells. Curr Atheroscler Rep. 2013 15(9):352.
     
  • Zaina S and Lund G. Atherosclerosis: cell biology and lipoproteins--panoramic views of DNA methylation landscapes of atherosclerosis. Curr Opin Lipidol. 2013 24(4):369-70
     
  • Zaina S, Lund G. Paternal transmission, cardiovascular risk factors and epigenetics. Curr Opin Lipidol. 2012 23:586-7
     
  • Zaina S, Lund G. Epigenetics: a tool to understand diet-related cardiovascular risk? J Nutrigenet Nutrigenomics. 2011 4:261-74.
     
  • Zaina S, Lund G. Integrating genomic and epigenomic information: a promising strategy for identifying functional DNA variants of human disease. Clin Genet. 2012 81:334-40
     
  • Zaina S, Lund G. Epigenetic memory, MBD2 and the endothelium. Curr Opin Lipidol. 2012 23:78-9.
     
  • Rangel-Salazar R, Wickström-Lindholm M, Aguilar-Salinas CA, Alvarado-Caudillo Y, Døssing KB, Esteller M, Labourier E, Lund G, Nielsen FC, Rodríguez-Ríos D, Solís-Martínez MO, Wrobel K, Wrobel K, Zaina S. Human native lipoprotein-induced de novo DNA methylation is associated with repression of inflammatory genes in THP-1 macrophages. BMC Genomics. 2011 25;12:582.
     
  • Lund G, Zaina S. Atherosclerosis: an epigenetic balancing act that goes wrong. Curr Atheroscler Rep. 2011 13:208-14.
     
  • Carpinteyro-Espín P, Jacinto-Ruíz S, Caballero-Vazquez P, Alvarado-Caudillo Y, Lund G, Rodríguez-Rios D, Martínez-García JA, Wrobel K, Wrobel K, Zaina S. Organomegaly and tumors in transgenic mice with targeted expression of HpaII methyltransferase in smooth muscle cells. Epigenetics. 2011 6:333-43.
     

Complete list of publications