viernes, 22 de septiembre de 2017
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We are working on the following projects

 

 

Gene interaction from evolution

Is it possible to predict gene interaction from genome evolution? Here, we are working towards the reconstruction of a network reflecting gene interaction based on the pattern of gene loss among genomes of Buchnera spp. This work is done in collaboration with Gil Bor from CIMAT.

Student responsible of the project: David Martínez Cano

 

 Symbiosis and Cellular Evolution

What are the causes of genome reduction in the chromatophore of Paulinella chromatophora? P. chromatophora is an amoeba that evolved an obligate symbiosis with a cyanobacteria. Genome comparison shows that the symbiotic cyanobacteria, i.e. the chromatophore, evolved by genome reduction from an ancestor of the cyanobacteria Synechococcus sp. WH5701.  We are developing a metabolic model of both cyanobacterias to understand to which extent genome reduction occurred to optimize the production of photosynthates for the amoeba-host.

Student responsible of the project: Cecilio Valadez Cano

 

Ancient mtDNA from maize

The domestication of maize is one of the key events leading to prehispanic civilizations of Mesoamerica. We are studying samples of ancient mtDNA to better undestand the process of domestication of teocintle into maize. This project is done in colaboration with Dr Jean-Philippe Vielle and Dr Rafael Montiel from UGA.

Responsible of the project: Bernardo Pérez
 

System biology of Synechococcus elongatus

Synechococcus elongatus is a genetically transformable, unicellular cyanobacterium; it is a model bacterium for studies of prokaryotic photosynthesis. Here we are working towards a metabolic model of this prokaryote. This work is done in collaboration with Dra Marcia Morales from UAM. 

Responsible of the project: Luis Alberto Martínez

 

 

Evolutionary Genomics of Phaseolus vulgaris

Which are the genomic phenomena behind the adaptation of common bean, Phaseolus vulgaris, to different environments all along the American continent? Have genomic flow and introgression events shaped the domestication process of Phaseolus vulgaris? This work is done in colaboration with Dr. Alfredo Herrera-EstrellaTo know more, click here.

Student responsible of the project: Martha Rendón Anaya

 

Transcriptomics of Agave

Agaves are virtually ubiquitous in Mexico and have prominent cultural and economic roles. However, there are relatively few efforts to understand the genomics of these plants. In this project we want to generate transcriptomes from different tissues of Agave tequilana, A. striata and A. victoriae-reginae to support the emergence of new research and improve understanding of these species at the molecular level. This work is done in collaboration with Dra. June Simpson.

Student responsible of the project: Emanuelle Avila De Dios

 

Evolution of sRNA in Polynucleobacter necessarius

Polynucleobacter necessarius is a beta-proteobacteria with multiple nucleoids and is also an endosymbiont of the protist Euplotes aediculatus.  Interestingly, P. necessarius has a close free living relative. Here we are studing the evolution of sRNA by comparative genomics of the free-living and endosymbiont strains.

Student responsible of the project: Isaac Martínez

 

 Bioinformatics

Are there protein orthographic rules? The order of amino acids in a polypeptide is clearly non random. Residues interact with their N- and C- neighbors, as well with other residues located far away in the sequence. Some of these interactions are important for maintaining the structure and function of proteins, and are ultimately important for the fitness of the organism. In this project we are interested in exploring the statistical composition of pairs of amino acids, and other statistical aspects of protein structure in order to look for “rules” of protein writing. This study is done in collaboration with Dr. Axel  Tiessen.

Student responsible of the project: Obed Ramirez