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We are working on the following projects

 

 

Testing the domino theory of gene loss

Is it possible to predict gene interaction from genome evolution? Here, we are working towards the reconstruction of a network reflecting gene interaction based on the pattern of gene loss among genomes of Buchnera spp. This work is done in collaboration with Gil Bor from CIMAT.

Student responsible of the project: David Martínez Cano

 

 Origin, function and evolution of HIP1

 

We are studying repeated sequences in cyanobacterial genomes, in particular, the function and evolution of the Highly-Iterated Palindrome 1 (HIP1). The hypothesis we are following is that HIP1 functions like a protein recognition motif. We are also asking how this sequence could be involved in molecular process like site-specific recombination and chromosome topology. 

Student responsible of the project: Ulises Rodríguez Cruz

 

 

 Evolution of gene regulatory networks

 

Gene regulatory networks are key for the evolution of phenotypic traits but how do these networks evolve? is still a question. To gain more information about this process, I studied the evolution of microRNA regulatory networks in Primates. We are studying changes in connectivity of these networks, or network rewiring, throughout the evolution of different Primates. Also we are exploring how these changes explain differential gene expression and other phenotypic differences between Hominoid Primates. This project is done in colaboration with Dr. Cei Abreu from Langebio.

Student responsible of the project: Gilberto Alejandro Álvarez Canales

 

 The nature of LUCA

In which conditions of temperature and oxygen did the last universal common ancestor (LUCA) thrived? Is it possible to infer these characteristics? Here we are working towards the reconstruction of LUCA gene sequences to learn about its oxigen tolerance and growth temperature. 

Student responsible of the project: Gilberto Pérez